Dr. Stefan Seidel

Projects

• CFD industrial scale protein extraction / Team member / Project completed

Publications

• Schneider, Samuel; Seidel, Stefan; Seefeldt, Andressa; Romang, Michael; Kastl, Simon; Gensel, Julia; Neumeyer, Thomas; John, Gernot Thomas; Eibl, Dieter,

  2023.

  3D printed, single-use bioreactor with integrated inline sensors for microbial and mammalian cell cultivation : a case study.

  Processes.

  11(11), pp. 3231.

  Available from: https://doi.org/10.3390/pr11113231

• Seidel, Stefan; Mozaffari, Fruhar; Maschke, Rüdiger W.; Kraume, Matthias; Eibl-Schindler, Regine; Eibl, Dieter,

  2023.

  Automated shape and process parameter optimization for scaling up geometrically non-similar bioreactors.

  Processes.

  11(9), pp. 2703.

  Available from: https://doi.org/10.3390/pr11092703

• Seidel, Stefan; Maschke, Rüdiger; Mozaffari, Fruhar; Eibl-Schindler, Regine; Eibl, Dieter,

  2023.

  Improvement of HEK293 cell growth by adapting hydrodynamic stress and predicting cell aggregate size distribution.

  Bioengineering.

  10(4), pp. 478.

  Available from: https://doi.org/10.3390/bioengineering10040478

• Seidel, Stefan; Eibl-Schindler, Regine; Eibl, Dieter,

  2022.

  Laboratory-independent exploration of stirred bioreactors and their fluid dynamics.

  Education for Chemical Engineers.

  42, pp. 80-87.

  Available from: https://doi.org/10.1016/j.ece.2022.10.001

• Kaiser, Stephan C.; Decaria, Paula N.; Seidel, Stefan; Eibl, Dieter,

  2022.

  Scaling‐up of an insect cell‐based virus production process in a novel single‐use bioreactor with flexible agitation.

  Chemie Ingenieur Technik.

  94(12), pp. 1950-1961.

  Available from: https://doi.org/10.1002/cite.202200103

• Seidel, Stefan; Maschke, Rüdiger; Kraume, Matthias; Eibl-Schindler, Regine; Eibl, Dieter,

  2022.

  CFD modelling of a wave-mixed bioreactor with complex geometry and two degrees of freedom motion.

  Frontiers in Chemical Engineering.

  4(1021416).

  Available from: https://doi.org/10.3389/fceng.2022.1021416

• Maschke, Rüdiger W.; Seidel, Stefan; Bley, Thomas; Eibl, Regine; Eibl, Dieter,

  2022.

  Determination of culture design spaces in shaken disposable cultivation systems for CHO suspension cell cultures.

  Biochemical Engineering Journal.

  177, pp. 108224.

  Available from: https://doi.org/10.1016/j.bej.2021.108224

• Seidel, Stefan; Eibl, Dieter,

  2021.

  Influence of interfacial force models and population balance models on the kLa value in stirred bioreactors.

  Processes.

  9(7), pp. 1185.

  Available from: https://doi.org/10.3390/pr9071185

• Seidel, Stefan; Maschke, Rüdiger; Werner, Sören; Jossen, Valentin; Eibl, Dieter,

  2020.

  Oxygen mass transfer in biopharmaceutical processes : numerical and experimental approaches .

  Chemie Ingenieur Technik.

  93(1-2).

  Available from: https://doi.org/10.1002/cite.202000179

• Seidel, Stefan; Schirmer, Cedric; Maschke, Rüdiger; Rossi, Lia; Eibl-Schindler, Regine; Eibl, Dieter,

  2023.

  Computational fluid dynamics for advanced characterisation of bioreactors used in the biopharmaceutical industry : part I: literature review

  .

  In:

  Ji, Guozhao; Dong, Jingliang, eds.,

  Computational Fluid Dynamics - Recent Advances, New Perspectives and Applications.

  London:

  IntechOpen Limited.

  pp. 53-82.

  Available from: https://doi.org/10.5772/intechopen.109848

• Seidel, Stefan; Schirmer, Cedric; Maschke, Rüdiger; Rossi, Lia; Eibl-Schindler, Regine; Eibl, Dieter,

  2023.

  Computational fluid dynamics for advanced characterisation of bioreactors used in the biopharmaceutical industry : part II: case studies

  .

  In:

  Ji, Guozhao; Dong, Jingliang, eds.,

  Computational Fluid Dynamics - Recent Advances, New Perspectives and Applications.

  London:

  IntechOpen Limited.

  pp. 83-98.

  Available from: https://doi.org/10.5772/intechopen.109849

• Seidel, Stefan; Maschke, Rüdiger W.; Kraume, Matthias; Eibl-Schindler, Regine; Eibl, Dieter,

  2023.

  Advanced numerical characterization of a wave-mixed bioreactor used in the biopharmaceutical industry [paper].

  In:

  Engineering Conferences International (ECI), Single Use Technologies VI: Established, Emergent, Agile, Sustainable?, Boston, USA, 10-13 September 2023.

• Seidel, Stefan; Maschke, Rüdiger W.; Mozaffari, Fruhar; Eibl-Schindler, Regine; Eibl, Dieter,

  2023.

  Prediction of the aggregate size distribution of HEK293 cells based on computational fluid dynamics [poster].

  In:

  Himmelfahrtstagung on Bioprocess Engineering 2023 - Novel production routes and processes for bio-pharmaceuticals and industrial bioeconomy, Weimar, Germany, 15-17 May 2023.

• Seidel, Stefan; Werner, Sören; Eibl, Dieter,

  2020.

  CFD for stirred bioreactors : analysis of different multiphase models to determine oxygen mass transfer [poster].

  In:

  Special Issue : 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020.

  10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020 : Processes for Future, Web-Konferenz, 21.-24. September 2020.

  Wiley.

  pp. 1324.

  Available from: https://doi.org/10.1002/cite.202055288

• Bayer, Marcus; Castan, Andreas; Eibl, Regine; Eibl, Dieter; Eisenkrätzer, Detlef; Fritz, Christina; Glaser, Robert; Glenz, Martin; Greller, Gerhard; Hug, Michelle; Kleebank, Sebastian; Kampmann, Markus; Krättli, Martin; Manser, Britta; Matuszczyk, Jens; Ottinger, Melanie; Schleper, Stefan; Schreiber, Marko; Seidel, Stefan; Selzer, Sebastian; Tanner, Markus; Teale, Misha; Tiemann, Karin,

  2020.

  Technical state-of-the-art and risk analysis on single-use equipment in continuous processing steps.

  Frankfurt am Main:

  DECHEMA, Gesellschaft für Chemische Technik und Biotechnologie e.V..

  ISBN 978-3-89746-226-7.

  Available from: https://doi.org/10.21256/zhaw-26357

• Seidel, Stefan; Schirmer, Cedric; Eibl, Dieter,

  2022.

  Integration of a drive system based on magnetic levitation technology to power a stirred bioreactor.

  In:

  Levitronix Bioprocessing Conference, Boston, USA, 2 June 2022.

  Available from: https://www.levitronix.com/app/uploads/2022/06/Stefan-2_1.mp4

• Seidel, Stefan; Werner, Sören; Eibl, Dieter,

  2020.

  Analysis of different multiphase CFD models for aerated stirred bioreactors.

  In:

  8th OpenFOAM Conference, virtual, 13-15 October 2020.

• Seidel, Stefan; Werner, Sören; Eibl, Dieter,

  2020.

  CFD for process engineering characterization.

  In:

  Levitronix Bioprocessing Conference, Webinar Part 3, 10 June 2020.

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